CRISPR-CasN enzymes

CRISPR-Cas systems are classified into several types and classes based on their protein components and their mechanisms of action. There are six major types (Type I, II, III, IV, V, and VI) and multiple subtypes within each type, based on the presence of specific Cas proteins and their respective functions. Here's a brief overview:

Classification and modular organization of CRISPR-Cas systems (Redrawn from Makarova et al., 2019. Nat Rev Microb)